Short Story – Why do lateral flow cassettes give problems?

Have you ever wondered what problems can be caused by Lateral Flow Cassettes

Though Lateral Flow Cassettes are worth using and buying, sometimes choosing the right rapid test cassette factories for buying these Lateral Flow Cassettes raises many questions.

You need to take care of the design and proper structuring of these Lateral Flow Cassettes while purchasing them from anywhere.

This won’t be a problem anymore because we have compiled a comprehensive guide for you that would list all the Lateral Flow Cassettes-related problems and their solutions for your information. 

Standard Approach to Lateral Flow Cassette Design

The typical procedure for lateral flow cassette (LFI cassette) design is for a stripe developer to provide the strip’s specs to an industrial design house or an engineering business that handles the Lateral Flow Cassette Design.

Short Story – Why do lateral flow cassettes give problems? 3

This usually occurs at the conclusion of the development process. After that, the cassette design process is iterated, progressing from fast prototype components through low-cost insert molds and finally to a production mold. 

The rapid test cassette factories recognized a long time ago that handling this aspect of the development process apart from the test may result in inconvenient delays and cost drift.

This is due to a number of factors, including the lateral flow cassette design and integration of the lateral flow cassette in the process, the need for multiple suppliers to develop the assay and the lateral flow cassette, and the typical process used by rapid test cassette factories, in which each lateral flow cassette is designed from the ground up using “industry standard” design features, low-cost molding, and assembly methods.

Some rapid test cassette factories have never been satisfied with that approach since they knew from experience that the cassette is a key component of product performance.

It’s crucial to the end product’s functioning, usability, and user pleasure, as well as branding and value proposition. This is not a component that should be overlooked.

So, why create another piece of cheap white plastic that is poorly molded and prone to failure while investing in the creation of a high-performance lateral flow test? Why should you stick to the “industry standard process”? 

That’s why we’ve created a lateral flow cassette design and development process that satisfies our clients’ demands for cost, quality, and performance in a simple and efficient manner.

Remedies Regarding Lateral Flow Cassette Design

Let’s look at some of the most prevalent problems and discuss some potential remedies for lateral flow cassette design.

The problem in the design and development of lateral flow devices is that the LFI cassette is treated as an afterthought. 

The majority of these errors are fatal to the product’s overall performance, and they can all be easily remedied by designing the lateral flow cassette to fit the strip architecture and the sample’s requirements.

Standard Practice does not result in well-designed or molded LFI cassettes.

The lateral flow OEM industry has depended on a fairly traditional technique for creating lateral flow cassette design for years. 

The assay creators engage an engineering firm to manufacture a cassette when the test has been developed to a certain degree. 

Based on early conceptual and functional designs, SLAs (stereolithographic, rapid prototype components) are utilized to “dial-in” the key pressure locations and closing pressures in a lateral flow cassette. The next step is generally to enter a low-cost mold insert (or MUD) that is used to manufacture test pieces.

This mold is tweaked until the components it creates function properly, which can take a long time. This is a time-consuming, laborious, iterative procedure that consumes lab, engineering, and machine shop resources and costs money.

Furthermore, in many situations, this procedure fails miserably. SLA components do not allow for accurate estimates of molded part closure, and the materials used are different from the final molded parts and react differently. Furthermore, this technique is frequently carried out by outside engineering firms who are unfamiliar with the test and how lateral flow cassette works.

Closure Process

Is it necessary to stress this even more in the lateral flow cassettes?

Many problems arise as a result of the industry-standard lateral flow cassette design and closure procedure. Pin and boss closures, generally with basic round pins and round holes, are still popular. 

In addition, throughout the design of the component, the closing procedure is frequently overlooked. 

This is a MAJOR blunder. The accuracy and repeatability of the closure and pressure points inside the lateral flow cassette are critical to the device’s overall operation.

The closing procedure is usually considered while designing a lateral flow cassette. When pins are used, they must always be round pins that go into round holes. Pins and bosses are strategically placed to prevent the strip from being over-or under-compressed. 

The guide features guarantee that the pins go into the holes properly and do not shear or distort during closing.

Bottom Line

These are some of the listed problems and remedies regarding lateral flow cassettes. Hope our post gave you an insightful understanding of making the LFI worth using and buying!